LIFR CHO
CBP74600
询 价
索取Protocol
产品描述
产品数据库
| I. Background | |
| LIFR 基因(LIF receptor subunit alpha)位于人类 5 号染色体短臂 5p13.1 区域,属于 I 型细胞因子受体家族,编码白血病抑制因子受体α亚基,广泛表达于脂肪、子宫内膜等 20 余种人体组织中。 该基因编码的跨膜蛋白可与 gp130 亚基结合形成高亲和力受体复合物,介导白血病抑 制因子(LIF)等多种配体的信号传导,调控细胞增殖、分化与存活过程,在骨骼形成、神 经细胞发育及自主神经系统正常功能维持中发挥关键作用。 |
|
| II. Description | |
| LIFR CHO 细胞,在 CHO-K1 细胞的基础上,稳定表达人 LIFR。 | |
| III. Introduction | |
| Expressed gene: | LIFR |
| Host Cell: | CHO |
| Stability: | 32 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | F12K+10%FBS+5 μg/ml Blasticidin |
| Mycoplasma Testing: | Negative |
| Storage: | Liquid nitrogen |
| Application(s): | Binding Assay,FACS |
| IV. Representative Data | |
Figure 1. Recombinant LIFR CHO constitutively expressing LIFR. |
|